Chapter 23: Aryl Halides
Aryl Grignards
Summary
Aryl Grignards are formed by the reaction of aryl halides (X= Cl, Br or I) with magnesium metal.
Typical solvents are normally anhydrous diethyl ether or tetrahydrofuran.
Halide reactivity : I > Br > Cl
Aryl Grignards undergo the sample types of reactions as alkyl Grignard reagents (
review
)
Organolithium reagents can also be made.
Aryl Grignard reactions allow for the introduction of C substituents other than via Friedel-Crafts
alkylation
or
acylation
reactions.
Related reactions
Preparation of Grignard reagents
Overview of Grignard reagents
©
Dr. Ian Hunt
, Department of Chemistry