etext Ch 19 : Carboxylic acids
Reactions to prepare carboxylic acids & carboxylic acid derivatives
Hydrolysis reactions of carboxylic acids derivatives esp. esters and amides.
Reactions of organometallic reagents with esters
Reactions of hydride reagents with esters
Hydride reduction of amides.
Reactions of nitriles with hydride and Grignard reagents

etext Ch 20 Enolates: why all the fuss ?  Enolates of aldehydes and ketones, esters.  Active methylene compounds.
pKa of enolates
Selected reactions of aldehyde and ketone enolates.... alkylations, the Aldol condensation
Selected reactions of ester enolates....   the Claisen condensation, Dieckmann condensation and other enolates....  overview
Decarboxylation of beta-ketoacid

Corresponds to L01 content modules 16 E-H (D2L content folder will be updated as we progress)

etext Ch 20: cont'd : Carboxylic acid derivatives : Relative reactivity.

Preparations of aldehydes and ketones including oxidation of alcohols

Reactions of aldehydes and ketones with various nucleophilic systems : compare / contrast mechanisms based on Nu strong vs weak
Reactions of hydride reagents (H- as nucleophile) with aldehydes and ketones to give alcohols.
Other reductions of aldehydes and ketones to CH2.

Reactions of organometallic reagents (C- as nucleophile) with aldehydes and ketones to give alcohols.
The Wittig reaction (used to prepare alkenes from aldehydes and ketones).
Reactions of aldehydes and ketones with water to form hydrates.
Reactions of aldehydes and ketones with alcohols to form acetals and ketals : application as "protecting groups", (protecting groups for alcohols).

etext Ch 17 :The Baeyer-Villager oxidation / reaction

Corresponds to L01 content modules 16 B-D (D2L content folder)

etext Ch 12 : How do aromatic substituents influence reactivity ? (contd)
Substituent effects, application and implication of substituent effects.

etext Ch 14: Introduction to organometallic reagents - a source of nucleophilic carbon, and hydride reagents - a source of nucleophilic hydrogen.
Organometallic compounds : what are they ? Recognising their reactivity. Review of their reactions with epoxides.

etext Ch 17: Aldehydes and ketones : review. Typical reaction mechanism : nucleophilic addition, Relative reactivity.
etext Ch 20: Carboxylic acid derivatives : Typical reaction mechanism : nucleophilic acyl substitution. Relative reactivity.

Corresponds to content modules 14 D-E, 15, 16A (D2L content folder)

Aromaticity Implications i.e. aromaticity impact on properties and reactions.

etext Ch 12 : Electrophilic aromatic substitution : why this pathway ?
Reactions of Aromatic systems. Table of reagents etc. for electrophilic aromatic substitution reactions. Examples of EAr. substitution reactions.
Reactions of other aromatic substitutents : reductions of C=O to CH₂
Reactions involving aromatic amines ArNH₂ - reduction of -NO₂, diazotisation ,reactions of diazonium salts
Reactions of other aromatic substitutents : reactions of the benzylic position
etext Ch 12 : How do aromatic substituents influence reactivity ?
Substituent effects, understanding, rationalising and recognising substituent effects

Corresponds to content modules 14A-C (D2L content folder)

How to analyse and design an organic synthesis

etext Ch11 Aromatic hydrocarbons and Arenes. What is aromaticity ? - resonance energy, aromaticity criteria
Other aromatic systems : PAHs, heteroaromatics , other hydrocarbons and annulenes.
Aromaticity criteria -  application to non-benzene systems (i.e. understanding aromaticity of molecules like pyrrole, pyridine, furan, etc and aromatic ions).
Other aromatic systems : PAHs, heteroaromatics , other hydrocarbons and annulenes.

Corresponds to content modules 12, 13A-C (D2L content folder)

etext Ch 10
Conjugated dienes, kinetic and thermodynamic control, 1,2- vs 1,4- (or direct vs conjugate) additions e.g. additions of hydrogen halides (HX)
Conjugated dienes : direct (1,2)- and conjugate (1,4)-additions of halogens (X2).
The Diels-Alder reaction : terminology, selectivity etc.

Corresponds to content modules 11B-D (D2L content folder)

Ozonolysis of alkenes and alkynes considering both oxidative and reductive work-ups.
Synthesis of 1,2-diols via oxidation of alkenes with KMnO₄ or OsO₄
Cyclopropanation reactions of alkenes
Study tool : make a table about the reactions (note no audio, just a table to complete from notes "review")
etext Ch 10 Polyenes: Terminology - conjugation, resonance, allylic systems : reactivity

Corresponds to video content modules 08C,D 09-11A,B (D2L content folder)

Halogenations of alkenes and alkynes.
Halohydration of alkenes (reactions with X2 / H2O and HOX).
An introduction to epoxides. Preparations : epoxidation of alkenes using peracids and synthesis from halohydrins via intramolecular Williamson type ether synthesis.
An introduction to the reactions of epoxides with various nucleophiles (strong vs weak), regio- and stereochemistry.

Corresponds to content modules 07, 08A-B (D2L content folder)

Radical addition of HBr to alkynes.
Hydration of alkenes : addition using H3O+ (i.e. aqueous acid) to give alcohols
Hydroboration / oxidation of alkenes
Oxymercuration / demercuration reactions of alkenes
Hydration of alkynes to ketones (via enol tautomerism)
Hydroboration / oxidation of alkynes.

Corresponds to content modules 05B, 06A-D (D2L content folder)

Catalytic hydrogenations of alkenes and alkynes.
Hydrohalogenation : addition of HX (HCl, HBr, HI) to alkenes to give alkyl halides (inc. radical addition of HBr)
Markovnikov's Rule - origins of the empirical observation (i.e. intermediate stability).
Hydrohalogenation : addition of HX to alkynes to give vinyl halides and alkyl dihalides.

Corresponds to content modules 04, 05A & B T (D2L content folder)

etext Ch 7: Isomer types (review), optical activity, polarimetry, specific rotation. Fischer projections, D/L nomenclature

etext Ch 6 Addition reactions of alkenes and etext Ch 9 addition reactions of alkynes
Start with a quick review of alkenes and alkynes: alkene nomenclature, alkyne nomenclature, structure, phys. properties, preparations of alkenes and alkynes.
Alkene and alkyne reactivities: what is their role in reactions ? Introduction to addition reactions. Transformations, regiochemistry, and stereochemistry.

Corresponds to content modules 02A, B & C (Optical Activity 1-3) + 03A & B (D2L content folder)

Introduction to Organic Chemistry II. What to expect, what to do, what not to do etc.
A little review of a few issues : key concepts from 351 Organic chemistry concept map, the families of reaction mechanisms, learning reactions.

etext Ch 7: Isomer types (review)

Corresponds to content modules 00A & B ("Intro & Prep" ), 01 (Learning Reactions), 02A (Optical Activity 1) (D2L content folder)