Chapter 21: Ester Enolates

There are 3 potentially important reactions of active methylenes (what are active methylenes ?)

• Reaction with alkyl halides (alkylation)
• Conjugate addition to a,b-unsaturated carbonyls (Michael addition)
• Loss of CO₂ (decarboxylation)

	Alkylation
	Michael addition
	Decarboxylation

© Dr. Ian Hunt, Department of Chemistry