1,2-Elimination reactions : E1 and E2 and E1cB mechanisms.

Dehydration of alcohols. Alkene stability. Regioselectivity (Zaitsev's rule) and stereoselectivity.
Dehydrohalogenations of alkyl halides inc. selectivity (regio- & stereo)

Conformational analysis of cycloalkanes (this builds off the molecular models laboratory experiment): terminology
Cycloalkanes....Cycloalkanes aren't planar, they are "puckered"
Cyclohexane : chair, boat and other conformers, axial,equatorial positions and substituent preferences.
Implications of conformational analysis in reactions (esp. eliminations of cyclohexyl halides)

Corresponds to content video modules (17A, 17B, 17C, 18) (D2L content folder, videos/templates will added when they are available and keeping pace with in-person L02, but posted after L02 occurs)

Reaction mechanisms: SN2 and SN1 reactions, carbocation intermediates
Examples of substitution reactions of alkyl halides
Examples of substitution reactions: substitution reactions of alcohols
Substitution reactions of alcohols using tosylates and thionyl chloride.
Solvent effects in SN reactions

Corresponds to content video modules 16A, 16B & 16C (D2L content folder)

Other issues in H-NMR : complex coupling patterns (contd)
13C-NMR : comparison with H-NMR, typical 13C chemical shifts, interpreting 13C spectra

Overview of Nucleophilic Substitution reactions
Nucleophiles and nucleophilicity, comparing nucleophilicity to basicity, leaving groups
Reaction mechanisms: SN2

Corresponds to content video modules 13E-H, 14,15 (D2L content folder)

Nuclear magnetic resonance (NMR), shielding, magnetic anisotropy
Characteristic chemical shifts, "levels" of information in H-NMR, integration, coupling patterns, coupling constants and the n+1 rule
Other issues in H-NMR : "accidental equivalence", typical coupling constants (J), complex coupling patterns

Corresponds to content video modules 13A, 13B, 13C & 13D (D2L content folder)

Mass spectrometry : basis and terminology isotope patterns (esp. for Cl & Br).
Nuclear magnetic resonance (NMR),  basic principles,  chemical shift

Corresponds to content video modules 12 & 13A (D2L content folder)

Alkane reactions: Radical substitution for the halogenation of alkanes and related systems (allylic and benzylic).
Spectroscopy : Background.  
Overview of the spectroscopic methods (MS, IR, H-NMR, 13C-NMR) : What do each of them tell you ? Deducing structures.
Infra-red spectroscopy : basic principles,  important absorptions

Corresponds to content video modules 09, 10, 11 (D2L content folder)

Monday Oct 14th, THANKSGIVING, UofC closed, no classes

Review oxidation states (not covered in lectures : should be first yr / high school review, template / worksheet provided facilitate the review)
Review Hydrocarbons : types of hydrocarbon, saturation and unsaturation.
Alkanes : alkanes and cycloalkanes : isomers, physical properties related to structure (intermolecular forces), thermodynamic stability of alkanes (linear vs branched).
Alkane reactions: Radical substitution for the halogenation of alkanes

Corresponds to content video modules 08A, 08B (D2L content folder)

Acidity and basicity : Rationalising acidity and basicity at the molecular level by looking at factors that affect these properties : the nature of the atom the H is attached to (electronegativity, size, charge, effect of hybridisation), stabilisation due to resonance and / or inductive effects. Minor factors: solvation and steric effects.
Application of acidity / basicity principles to reactions based on pKa.

Corresponds to content video modules 07A, 07B, 07C (D2L content folder)

Monday Sept 30th, Truth and Reconciliation Day, UofC closed, no classes.

The families of reaction mechanisms.
Formal charges (assigning and recognising based on structures and curly arrows). Acidity and basicity : review definitions, Ka and pKa etc.
The acidity ladder.

Corresponds to content video modules 06A, 06B (D2L content folder)

Resonance - implications of structure, recognising and ranking resonance contributors
Resonance - contd: examples of "resonance in action"
Mastering mechanisms : Curly arrows : make them talk to you !

Corresponds to content video modules 05, 06A (D2L content folder)

Continue: molecular geometries (using VSEPR)
What happens at the molecular level when atoms interact to form bonds ?
Electron density animation of 2 interacting H atoms -> H₂
How do covalent bonds form and what are molecular orbitals ? Bonding and anti-bonding orbitals. Why no He₂ ? 
Bonding in organic systems : hybridisation for hydrocarbons, and then heteroatom systems. (Flash animation for visualising hybridisation).
Bonding in alkanes, alkenes and alkynes.

Corresponds to content video modules 03D, 04A, 04B (D2L content folder)

Continue the language of organic chemistry: "text and symbols" : Drawing line diagrams. Curly arrows.
Structure and Bonding: etext Ch1 : The relationship of structure and function. Atomic structure and terminology. Bonding, bond types, bond properties, molecular geometries (VSEPR), acidity and pKa.

Corresponds to content video modules 01, & 02A, 03A, 03B, 03C (D2L content folder)

Introduction to Organic Chemistry I. Overview of course components, using TopHat etc.
What to expect, what to do, what not to do etc.  How to work for your personal success. Our expectations.
Chemistry 351 concept map (the big picture connecting the concepts together).
The language of organic chemistry: "text and symbols"
Definitions of key terms: functional group, nucleophile, electrophile, leaving group, electronegativity, resonance.

CHEM351F24 lectures start Wed Sept 4th 2024.

Corresponds to content video modules 00, 01, & 02A (D2L content folder)