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Chapter 20: Carboxylic
Acid Derivatives. Nucleophilic Acyl Substitution
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Interconversion Reactions
of Acid Anhydrides
![conversion of acid anhydrides to other carboxylic acid derivatives](anhydriderxn.gif) |
esters
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acids
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amides
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Reaction type: Nucleophilic
Acyl Substitution
Summary
- Acid anhydrides are the second
most reactive of the carboxylic acid derivatives and can therefore, be fairly
readily converted into the other less reactive carboxylic acid derivatives
(see above).
- A base in often added to neutralise
the carboxylic acid by product that is formed.