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Basic α-Halogenation of Aldehydes and Ketones
Summary
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Step 1:
First, an acid-base reaction. Hydroxide functions as a base and removes the acidic α-hydrogen giving the enolate. |
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Step 2:
The nucleophilic enolate reacts with the halide giving the halogenated ketone and a bromide ion. |
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© Dr. Ian Hunt, Department of Chemistry |