Chapter 17: Aldehydes and Ketones. Nucleophilic Addition to C=O |
Hydride Reductions of
Aldehydes and Ketones
(review of Chapter 15)
Reactions usually in Et2O or THF followed by H3O+
work-ups
Reaction type: Nucleophilic Addition
Summary
NUCLEOPHILIC
ADDITION OF LiAlH4 TO AN ALDEHYDE |
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Step 2: This is the work-up step, a simple acid/base reaction. Protonation of the alkoxide oxygen creates the primary alcohol product from the intermediate complex. |
© Dr. Ian Hunt, Department of Chemistry |