Return to Contents Chapter 27: Amino Acids, Peptides and Proteins Ch 27 contents
Peptide Synthesis : Forming the peptide bond
a reactive nitro ester that can be used to promote amide formation

QUESTIONS

 
  • Why don't amines and carboxylic acids react well to give amides ?
  • ANSWER
     
  • What better ways are there to make simple amides ?
  • ANSWER
     
  • Why is the nitrophenyl ester better in the coupling reaction than a simple methyl ester ?
  • ANSWER

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    organic chemistry © Dr. Ian Hunt, Department of Chemistry University of Calgary