Return to Contents Chapter 16: Ethers, Epoxides and Sulfides Ch 16 contents

SN2 type Reactions of Epoxides

SN2 type ring opening reaction of epoxides
Reaction type:  Nucleophilic Substitution (SN2)
Scenario 1:
The Nu attacks the more substituted C of the epoxide at 180o to the C-O bond that breaks.
which pathway occurs ?
Scenario 2:
The Nu attacks the least hindered end of the epoxide at 180o to the C-O bond that breaks.
Summary
previous page
next page
organic chemistry © Dr. Ian Hunt, Department of Chemistry University of Calgary