13C-NMR contd : typical 13C chemical shifts, interpreting 13C spectra

Overview of Nucleophilic Substitution reactions
Nucleophiles and nucleophilicity, comparing nucleophilicity to basicity, leaving groups
Reaction mechanisms: SN2 and SN1 reactions, carbocation intermediates
Examples of substitution reactions of alkyl halides

Corresponds to content video modules 13E-H, 14 (TBA) (D2L content folder, videos/templates will added when they are available and keeping pace with in-person L02, but posted after L02 occurs)

Nuclear magnetic resonance (NMR), shielding, magnetic anisotropy
Characteristic chemical shifts, "levels" of information in H-NMR, integration, coupling patterns, coupling constants and the n+1 rule
Other issues in H-NMR : "accidental equivalence", typical coupling constants (J), complex coupling patterns
13C-NMR : comparison with H-NMR

Corresponds to content video modules 13A-D & TBA (D2L content folder)

Mass spectrometry : basis and terminology isotope patterns (esp. for Cl & Br), molecular ion and molecular weight.
Nuclear magnetic resonance (NMR),  basic principles,  chemical shift, shielding

Corresponds to content video modules 12, 13A, 13B and TBA (D2L content folder)

Alkane reactions: Radical substitution for the halogenation of alkanes : Related systems (allylic and benzylic).
Spectroscopy : Background.  
Overview of the spectroscopic methods (MS, IR, H-NMR, 13C-NMR) : What do each of them tell you ? Deducing structures.
Infra-red spectroscopy : basic principles,  important absorptions

Corresponds to content video modules 09, 10, 11 (D2L content folder)

Monday Oct 13th, THANKSGIVING, UofC closed, no classes

Alkanes : alkanes and cycloalkanes : isomers, physical properties related to structure (intermolecular forces), thermodynamic stability of alkanes (linear vs branched).
Alkane reactions: Radical substitution for the halogenation of alkanes and related systems (allylic and benzylic).

Review oxidation states (not covered in lectures : should be first yr / high school review, template / worksheet provided facilitate the review)

Corresponds to content video modules 08A, 08B (D2L content folder)

Wk 6
(Oct 6-10)

Rationalising acidity and basicity at the molecular level by looking at factors that affect these properties contd : the nature of the atom the H is attached to (electronegativity, size, charge, effect of hybridisation), stabilisation due to resonance and / or inductive effects. Minor factors: solvation and steric effects.
Application of acidity / basicity principles to reactions based on pKa.
Review Hydrocarbons : types of hydrocarbon, saturation and unsaturation.
Alkanes : alkanes and cycloalkanes : isomers, physical properties related to structure (intermolecular forces)

Corresponds to content video modules 07A, 07B, 07C, 08A (D2L content folder)

Mastering mechanisms : Curly arrows : make them talk to you !The families of reaction mechanisms.
Formal charges (assigning and recognising based on structures and curly arrows). Acidity and basicity : review definitions, Ka and pKa etc. The Henderson-Hasselbalch equation. The acidity ladder.
Rationalising acidity and basicity by looking at factors that affect these properties at the molecular level : The nature of the atom the H is attached to (electronegativity, size, charge, effect of hybridisation), stabilisation due to resonance etc.

Corresponds to content video modules 06A, 06B, 07A, 07B (D2L content folder)

Corresponds to content video modules 04B, 05, 06A (D2L content folder)

Continue: bond properties, molecular geometries, acidity and pKa, molecular geometries (using VSEPR)
What happens at the molecular level when atoms interact to form bonds ?
Electron density animation of 2 interacting H atoms -> H₂
How do covalent bonds form and what are molecular orbitals ? Bonding and anti-bonding orbitals. Why no He₂ ? 
Bonding in organic systems : hybridisation for hydrocarbons, and then heteroatom systems. (Flash animation for visualising hybridisation).

Corresponds to content video modules 03B, 03C, 03D, 04A (D2L content folder)

Chemistry 351 concept map (the big picture connecting the concepts together).
The language of organic chemistry: "text and symbols", examples.
Definitions of key terms: functional group, nucleophile, electrophile, leaving group, electronegativity, resonance.
Drawing line diagrams. Curly arrows.
Structure and Bonding: etext Ch1 : The relationship of structure and function. Atomic structure and terminology. Bonding, bond types.

Corresponds to content video modules 02A, 02B, 03A (D2L content folder)

Introduction to Organic Chemistry I. Overview of course components, using TopHat etc.
What to expect, what to do, what not to do etc.  How to work for your personal success. Our expectations.
What is organic chemistry ? What makes it difficult, how are we going to tackle it ?

CHEM351F25 lectures start Wed Sept 3rd 2025.

Corresponds to content video modules 00 & 01 (D2L content folder)